The why and how of thymocyte negative selection
نویسندگان
چکیده
منابع مشابه
DR3 regulates negative selection during thymocyte development.
DR3 (Ws1, Apo3, LARD, TRAMP, TNFSFR12) is a member of the death domain-containing tumor necrosis factor receptor (TNFR) superfamily, members of which mediate a variety of developmental events including the regulation of cell proliferation, differentiation, and apoptosis. We have investigated the in vivo role(s) of DR3 by generating mice congenitally deficient in the expression of the DR3 gene. ...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2006
ISSN: 0952-7915
DOI: 10.1016/j.coi.2006.01.001